AJT Highlights

AJT June 2024 Editors' Picks

Host Roz is joined by AJT Associate Editor Orla Morrissey, MD (Monash University) and AJT Editorial Fellow Elena-Bianca Barbir, MD (Mayo Clinic-Rochester).

[3:16] The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation

[19:14] Association between cytomegalovirus viremia and long-term outcomes in lung transplant recipients

[35:40] Genetic versus self-reported African ancestry of the recipient and neighborhood predictors of kidney transplantation outcomes in 2 multiethnic urban cohorts

[EDITORIAL] Untangling genetic and environmental risks in kidney transplant outcomes: The interplay of self-identified race, genetic ancestry, monogenic risk alleles, and socioeconomic factors

[45:15] Low-affinity CD8+ T cells provide interclonal help to high-affinity CD8+ T cells to augment alloimmunity

[53:44] Outcomes in solid organ transplant recipients with a pretransplant diagnosis of melanoma

The impact of the 2018 change in heart allocation and what the heart community can learn from experiences with continuous distribution of lung

In this AJT specialty podcast, Luise Holzhauser, hosts Shelley Hall and Marie Budev to discuss the impact of the 2018 change in heart allocation and what the heart community can learn from experiences with continuous distribution of lung.

AJT May 2024 Editors' Picks

Host Roz is joined by AJT Executive Guest Editor Nadim Mahmud, MD, MPH (University of Pennsylvania) and AJT Editorial Fellow Tina Marinelli, MBBS, MPH&TM,  FRACP (Royal Prince Alfred Hospital).

 

[03:10] Semidirected Living Donors in Israel: Sociodemographic Profile, Religiosity, and Social Tolerance

 

[11:54] TCRseq Reveals Selected Donor-reactive CD8+ T cell Clones Resist Anti-Thymocyte Globulin Depletion after Kidney Transplantation

 

[18:47] Natural killer cell functional genetics and donor-specific antibody-triggered microvascular inflammation

 

[26:36] Surgical site infections after kidney transplantation are independently associated with graft loss

 

[38:26] Introduction to Virtual Special Issue, Insights into ACLF: From Pathogenesis to Interventions

 

[39:21] Immunopathogenesis of acute on chronic liver failure

 

[43:43] Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!

AJT April 2024 Editors' Picks

Host Roz is joined by AJT Editor-in-Chief Emeritus Allan Kirk, MD, PhD, (Duke University) and AJT Editorial Fellow Laura Binari, MD (Vanderbilt University).

[2:34] Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates

[14:09] A2/A2B to B deceased donor kidney transplantation in the Kidney Allocation System era

[24:01] Xenotransplantation Papers

[25:07] Xenotransplantation experiments in brain-dead human subjects–A critical appraisal

[28:11] The decedent model: A new paradigm for de-risking high stakes clinical trials like xenotransplantation

[32:45] Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry

AJT March 2024 Editors' Picks

Host Roz is joined by AJT Editorial Board Member Alexandre Loupy, MD, PhD (Necker Hospital) and AJT Editorial Fellow Thiago J Borges, PhD (Massachusetts General Hospital).

[2:39] Transplanting old organs promotes senescence in young recipients

[11:33] The Banff 2022 Kidney Meeting Report: Reappraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics

[15:45] The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff Classification for renal allografts

(Editorial) [18:12] The Banff process—Reloaded: A joint initiative from the Banff Foundation for Allograft Pathology and the American Journal of Transplantation

[20:25] Antiobesity pharmacotherapy to facilitate living kidney donation

[27:04] Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients

AJT February 2024 Editors' Picks

Host Roz is joined by AJT Editorial Board Member John Greenland, MD, PhD (University of California, San Francisco) and AJT Editorial Fellow David Cron, MD, MS (Massachusetts General Hospital).

[2:53] Pure laparoscopic donor hepatectomy: Experience of 556 cases at Seoul National University Hospital

[11:26] Smoking exposure-induced bronchus-associated lymphoid tissue in donor lungs does not prevent tolerance induction after transplantation & Aging exacerbates murine lung ischemia-reperfusion injury by excessive inflammation and impaired tissue repair response

[20:28] Augmenting the Unites States transplant registry with external mortality data: A moving target ripe for further improvement

(Editorial) How hard are the hard outcomes reported in national transplant registries?

[32:25] Maintaining the permanence principle of death during normothermic regional perfusion in controlled donation after the circulatory determination of death: Results of a prospective clinical study

The impact and implications of the kidney allocation system (KAS 250) over kidney allocation in the United States

The podcast discusses the impact and implications the kidney allocation system (KAS 250) has had over kidney allocation in the United States, focusing on the effect on operational challenges, cold ischemic times, delayed graft function, and organ discard rates.

Guest speakers include Joel Adler (Dell Medical School, University of Texas in Austin) and John Friedewald (Northwestern Memorial Hospital).

AJT January 2024 Editors’ Picks

Host Roz is joined by AJT Editorial Board Member Michael Mengel, MD (University of Alberta) and AJT Editorial Fellow Kazem Fallahzadeh, MD (Emory University).

[2:43] Recurrent atypical antiglomerular basement membrane nephritis in the kidney transplant

[14:26] Pretransplantation coronavirus disease 2019 vaccination requirements: A matched case-control study of factors associated with waitlist inactivation

(Editorial) Coronavirus disease 2019 vaccine mandates and the Owl of Minerva

[21:45] Incomplete tissue product tracing during an investigation of a tissue-derived tuberculosis outbreak

[29:48] Risk for graft loss in pediatric and young adult kidney transplant recipients due to recurrent IgA nephropathy

[37:07] De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy

AJT Decmber 2023 Editors’ Picks

Host Roz is joined by AJT Editorial Board Member Emily Blumberg, MD (University of Pennsylvania) and AJT Editorial Fellow Dempsey Hughes, MD (Northwestern Medicine).

[03:03] Predicting post–liver transplant outcomes in patients with acute-on-chronic liver failure using Expert-Augmented Machine Learning

[10:34] Clinical features, treatment, and outcomes of mpox in solid organ transplant recipients: A multicenter case series and literature review

[14:05] First case of rapidly fatal mpox from secondary (household) transmission in a kidney transplant recipient

[15:28] A joint program of antimicrobial stewardship and hospital-acquired infection control to reduce healthcare-associated infections after kidney transplantation: The Hipomenes study

[22:55] A rational approach to guide cost-effective de novo donor-specific antibody surveillance with tacrolimus immunosuppression

[30:04] (Editorial) Personalizing kidney transplant donor-specific antibody surveillance: The devil is in the details

[33:20] Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial

Kidney Utilization and Organ Procurement Organization Performance

In this specialty podcast, Arielle Cimeno, hosts Raymond Lynch and Amit Mathur to discuss recent trends and new initiatives to assess kidney utilization and organ procurement organization performance.